Toluidine blue stain (Mohs rapid margin staining)
Cationic metachromatic dye used as a fast alternative to hematoxylin-eosin for staining frozen Mohs sections; produces a metachromatic pattern around basal cell carcinoma that helps delineate the margin.
How it is used
Intraoperative histological staining of frozen Mohs sections when speed is prioritized over cytological detail.
Clinical tip
A comparative study between hematoxylin-eosin and toluidine blue in 23 cutaneous tumors found no significant diagnostic differences between the two stains.
Sources
This entry is part of the Instriq catalog, researched and written per specialty from real web research -- never generated or invented without verification -- and reviewed skeptically and independently before publication. How this catalog is written.